Dynamic AFM image of a live rat mesenchymal stem cell showing both linear and geodesic arrangements of the F-actin cytoskeleton. The high energy dissipation indicated at the geodesic vertices confirms the prediction of Lazarides (J. Cell. Biol. 68, 202-219 (1976)) that the vertices should have higher flexibility based on the absence of tropomyosin and myosin at these junctions. 90µm scan. For more information, see HFSP Journal, 1, 181-191 (2007). Image courtesy of Suzi Jarvis and colleagues, Conway Institute for Biomolecular and Biomedical Research, University College Dublin (www.nanofunction.org).
Back
